{"id":286,"date":"2020-03-27T11:12:44","date_gmt":"2020-03-27T14:12:44","guid":{"rendered":"https:\/\/brazmedchem.org\/2022\/?page_id=286"},"modified":"2022-09-21T01:05:37","modified_gmt":"2022-09-21T04:05:37","slug":"scientific-program","status":"publish","type":"page","link":"https:\/\/brazmedchem.org\/2022\/scientific-program\/","title":{"rendered":"Scientific Program"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text]Sunday, 25th September 2022<\/b><\/p>\n\n\n\n\n\n\n
2:00-6:00 p.m.<\/b><\/td>\nConference Registration<\/b><\/td>\n9:00-12:00 a.m.<\/b><\/td>\nShort course: Drug Design – Jean Leandro dos Santos<\/b>
\nInova\u00e7\u00e3o em f\u00e1rmacos no ambiente acad\u00eamico com foco na otimiza\u00e7\u00e3o molecular<\/a><\/strong><\/td>\n<\/tr>\n
6:00-6:30 p.m.<\/b><\/td>\nOpening Ceremony<\/td>\n12:00-2:00 p.m.<\/b><\/td>\nLunch<\/td>\n<\/tr>\n
6:30-7:30 p.m.<\/b><\/td>\nOpening Conference – Dr. Michael J. Sofia<\/b>
\n\u201cThe Discovery of Antivirals to Cure Chronic Viral Hepatitis\u201d<\/i><\/b><\/a><\/td>\n		2:00-5:00 p.m.<\/b><\/td>\nShort course: Drug Design – Jean Leandro dos Santos
\nInova\u00e7\u00e3o em f\u00e1rmacos no ambiente acad\u00eamico com foco na otimiza\u00e7\u00e3o molecular<\/a><\/em><\/strong>
\n<\/b><\/td>\n<\/tr>\n
7:30-11:30 p.m.<\/b><\/td>\nWelcome Cocktail<\/td>\n<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Monday, 26th September 2022<\/b><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Session 1: Natural Products-based Drug Discovery<\/b><\/p>\n

Chair: Alexandre Orsato \u2013 Londrina State University, Brazil<\/b><\/td>\n

\n

Session 2: Computer-aided Drug Design (CADD)<\/b><\/p>\n

Chair: Marcelo Castilho \u2013 Federal University of Bahia, Brazil<\/b><\/td>\n<\/tr>\n

9:00-9:45 a.m.<\/b><\/td>\nScott Smid (University of Adelaide, Australia)<\/b>
\nThe Phytochemical Diversity of Cannabis: Exploring this \u2018Potpourri\u2019 of Potential for Development of Cannabinoid-based medicines<\/b><\/em><\/a><\/td>\n		9:00-9:45 a.m.\u00a0<\/b><\/td>\nStefano Alcaro (Univ. Magna Gr\u00e6cia of Catanzaro, Italy)<\/b>
\nCan in silico<\/i> Medicinal Chemistry help the drug discovery of natural compounds?<\/b><\/a><\/td>\n<\/tr>\n
9:45-10:15 a.m.<\/b><\/td>\nLucindo Quintans Jr. (Federal Univ. of Sergipe, Brazil)<\/b>
\nCan we use terpenes in chronic pain models? How cyclodextrins can help it?<\/strong><\/a><\/em><\/b><\/td>\n		9:45-10:30 a.m.<\/b><\/td>\nAlan Talevi, PhD \u2013 (University of La Plata, Argentina)<\/b>
\nLIDeB Tools: a Latin American resource of freely available, open-source cheminformatics apps to assist drug discovery projects<\/a><\/strong><\/em><\/td>\n<\/tr>\n
10:15-10:45 a.m.<\/b><\/td>\nLaurent Picot (University of La Rochelle, France)<\/b>
\nPlant and algal natural products for tumor and antimicrobial phototherapy: an overview of species, photototoxic molecules and innovations.<\/a><\/b><\/td>\n		10:30-11:00 a.m.<\/b><\/td>\nCoffee Break<\/td>\n<\/tr>\n
10:45-11:15 a.m.<\/b><\/td>\nCoffee break<\/td>\n11:00-11:45 a.m.<\/b><\/td>\nHugo Verli (Federal Univ. of Rio Grande do Sul, Brazil)<\/b>
\nHow molecular flexibility can enhance drug discovery?<\/b><\/em><\/a><\/td>\n<\/tr>\n
11:15-11:45 a.m.<\/b><\/td>\nRaphael Grougnet (University of Paris Descartes, France)<\/b>
\nImplementation, development, biological evaluations and SAR of a library of polymethoxyflavones<\/strong><\/a><\/em><\/b><\/td>\n		11:45-12:00 a.m.<\/b><\/td>\nFlash Presentation: \u201cMaximization of SARS-CoV-2 neutralization by antibodies through Monte Carlo optimization\u201d – Micael D. L. Oliveira <\/b>(Federal University of Amazonas, Brazil)<\/a><\/td>\n<\/tr>\n
11:45-12:00 a.m.<\/b><\/td>\nFlash Presentation: \u201cIn silico interaction of organic propolis molecules with targets related to oral mucositis\u201d – Mikaela L. de Souza <\/b>(Federal University of Alfenas, Brazil)\u00a0<\/span><\/a><\/td>\n12:00-2:00 p.m.<\/b><\/td>\nLunch<\/td>\n<\/tr>\n
12:00-2:00 p.m.<\/b><\/td>\nLunch<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\n

Session 3: MedChem for Drug Addiction<\/b><\/p>\n

Chair: Gisele C. Goulart \u2013 Federal University of Minas Gerais, Brazil<\/b><\/td>\n

\n

Session 4: Pre-clinical Development<\/b><\/p>\n

Chair: Arthur K\u00fcmmerle \u2013 Federal Rural Univ. of Rio de Janeiro, Brazil<\/b><\/td>\n<\/tr>\n

2:00-2:45 p.m.<\/b><\/td>\nFabr\u00edcio A. Moreira <\/b>(Federal Univ. of Minas Gerais, Brazil)<\/b>
\nMedChem for Drug addiction: Targeting the endocannabinoid system<\/b><\/a><\/em><\/td>\n		2:00-2:45 p.m.<\/b><\/td>\nMarco Aur\u00e9lio Martins (Fiocruz, Brazil)<\/b>
\nGold nanoparticles for the treatment of glucocorticoid insensitive asthma: what we have learned so far?<\/strong><\/a><\/em><\/b><\/td>\n<\/tr>\n
2:45-3:30 p.m.<\/b><\/td>\nFrederico D. Garcia (Federal Univ. of Minas Gerais, Brazil)<\/b>
\nPreclinical and innovative uses of anticocaine vaccine: the UFMG-V4N2<\/strong><\/a><\/em><\/td>\n		2:45-3:30 p.m.<\/b><\/td>\nStefan Laufer (University of T\u00fcbingen, Gemany)<\/b>
\nDISCOVERY AND DEVELOPMENT OF A MKK-4 INHIBITORS TO INCREASE LIVER REGENERATION<\/em><\/a><\/b><\/td>\n<\/tr>\n
3:30-3:45 p.m.<\/b><\/td>\nFlash Presentation: \u201cPharmacophore mapping combined with dbCICA reveals new insights on ?4?2 and ?7 nicotinic acetylcholine receptors ligand design<\/b>\u201d – Nailton M. Nascimento-J\u00fanior, Ph.D. (S\u00e3o Paulo State University, Brazil)<\/a><\/td>\n3:30-3:45 p.m.<\/b><\/td>\nFlash Presentation: \u201cAntitrypanosomal Benzoxazinone Series: Hit-to-Lead Campaign and Multiparametric Optimization\u201d – <\/b>Maria C. Mollo (State University of Campinas, Brazil)<\/a><\/td>\n<\/tr>\n
3:45-4:15 p.m.<\/b><\/td>\nCoffee Break<\/td>\n3:45-4:15 p.m.<\/b><\/td>\nCoffee Break<\/td>\n<\/tr>\n
\n

Session 5: MedChem for Neglected Diseases<\/b><\/p>\n

Chair: Elizabeth I. Ferreira \u2013 University of S\u00e3o Paulo, Brazil<\/b><\/a><\/td>\n

\n

Session 6: MedChem for Neurodegenerative Diseases<\/b><\/p>\n

Chair: Lorane H. Melim \u2013 Federal University of Amap\u00e1, Brazil<\/b><\/td>\n<\/tr>\n

4:15-5:00 p.m.<\/b><\/td>\nRafaela Salgado Ferreira
\n<\/b><\/b>Cruzipains as a target for Chagas disease: inhibitor discovery and characterization of subtypes<\/b><\/em><\/a><\/td>\n		4:15-5:00 p.m.<\/b><\/td>\nMaria Laura Bolognesi (University of Bologna, Italy)<\/b>
\nMulti-target-directed ligands to combat neurodegenerative diseases \u2014 Past, present and future<\/i><\/b><\/a><\/td>\n<\/tr>\n
5:00-5:45 p.m.<\/b><\/td>\nRafael Guido (University of S\u00e3o Paulo, Brazil)<\/b>
\nDiscovery of Plasmodium falciparum Inhibitors as Lead Candidates for Malaria<\/a><\/em><\/strong><\/td>\n		5:00-5:45 p.m.<\/b><\/td>\nAndrea Tarozzi (University of Bologna, Italy)
\nTargeting the NLRP3 inflammasome in neurodegenerative diseases<\/a><\/em>
\n<\/b><\/td>\n<\/tr>\n
5:45-6:00 p.m.<\/b><\/td>\nFlash Presentation: \u201cCheminformatics-driven identification of new antiplasmodial hits effective against asexual and sexual stages\u201d – <\/b>Sabrina S. Mendon\u00e7a (Federal University of Goias, Brazil)<\/a><\/td>\n5:45-6:00 p.m.<\/b><\/td>\nFlash Presentation: \u201cTriazole grandisin analog prevents memory deficit by antioxidant effects in an Alzheimer\u2019s Disease model\u201d <\/b>– Erick Y. M. Rodrigues (Federal University of Mato Grosso do Sul, Brazil)<\/a><\/td>\n<\/tr>\n
6:00-8:00 p.m.<\/b><\/td>\nPoster Session 1<\/b><\/td>\n6:00-8:00 p.m.<\/b><\/td>\nPoster Session 1<\/b><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Tuesday, 27th September 2022<\/b><\/p>\n\n\n\n\n\n\n\n\n\n\n
\n

BrazMedChem Awards<\/b><\/p>\n

Chair: Gustavo Trossini \u2013 President of the Medicinal Chemistry Division \u2013 Brazilian Society of Chemistry<\/b><\/td>\n

\n

BrazMedChem – Scientific Activities for the Local Community<\/b><\/p>\n

Chairs: Aline Guerra – Federal University of Rio de Janeiro, Brazil<\/b><\/p>\n

Claudio Viegas Jr. \u2013 Federal University of Alfenas, Brazil\u00a0<\/span><\/b><\/p>\n

\u00c2ngelo de F\u00e1tima – Federal University of Minas Gerais, Brazil<\/b>\u00a0<\/span><\/b><\/td>\n<\/tr>\n

9:00-9:30 <\/b>a.m.<\/b><\/td>\nYoung BrazMedChem Awards<\/td>\n9:00-10:00 a.m.<\/b><\/td>\nAwards’ Ceremony of the BrazMedChem Writing Olympics\u00a0<\/span><\/td>\n<\/tr>\n
9:30-10:00 <\/b>a.m.<\/b><\/td>\nVanguard BrazMedChem Awards<\/td>\n10:00 a.m.- 6 p.m.<\/b><\/td>\nScientific Activities for Local Community<\/td>\n<\/tr>\n
10:00-11:00 <\/b>a.m.<\/b><\/td>\nSenior BrazMedChem Awards<\/td>\n2:00-3:00 p.m.<\/b><\/td>\nTheatrical Presentation for Local Community
\nCi\u00eancia \u00e9 Vida<\/strong><\/span><\/a>
\n(The presentation will be only in Portuguese)<\/span><\/td>\n<\/tr>\n
11:00-1:00 p<\/b>.m.<\/b><\/td>\nCoffee Break<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
1:00-2:00 p.m.<\/b><\/td>\nLunch<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
2:00-7:00 p.m.<\/b><\/td>\nFree Time<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
7:00-8:00 p.m.<\/b><\/td>\nTheatrical Presentation for BrazMedChem Community
\nCi\u00eancia \u00e9 Vida<\/strong><\/span><\/a>
\n(The presentation will be only in Portuguese)<\/span><\/td>\n		<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Wednesday, 28th September 2022<\/b><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Gender in Medicinal Chemistry: How to make a successfull carreer in Academy and Industry?<\/b><\/td>\n<\/tr>\n
9:00-9:20 a.m.<\/b><\/td>\nSpeaker 1: Elizabeth Igne Ferreira (University of S\u00e3o Paulo)<\/b>
\nMedicinal Chemistry: advances and challenges<\/a><\/em><\/strong><\/td>\n<\/tr>\n
9:20-9:40 a.m.<\/b><\/td>\nSpeaker 2: Maria Em\u00edlia Sousa (University of Porto, Portugal)<\/b>
\nResearch, Academia, and Outreach Activities in Portugal: a Personal Experience<\/strong><\/a><\/em><\/td>\n<\/tr>\n
9:40-10:00 a.m.<\/b><\/td>\nSpeaker 3: J\u00falia L. Monteiro\u00a0(EUROFARMA)<\/b>
\nPre-Clinical Development at Eurofarma: how a Brazilian Pharmaceutical Company is investing in Drug Discovery?<\/b><\/a><\/em><\/td>\n<\/tr>\n
10:00-10:30 a.m.<\/b><\/td>\nDiscussion<\/td>\n<\/tr>\n
10:30 a.m.-12:30 p.m.<\/b><\/td>\nCoffee Break\/Poster Session 2<\/b><\/td>\n<\/tr>\n
12:30-2:00 p.m.<\/b><\/td>\nLunch<\/td>\n<\/tr>\n
\n

Session 7: Multi-target Directed Ligands<\/b><\/p>\n

Chair: Claudio Viegas Jr. \u2013 Federal University of Alfenas, Brazil<\/b><\/td>\n

\n

Session 8: MedChem for Infectious Diseases<\/b><\/p>\n

Chair: \u00c2ngelo de F\u00e1tima \u2013 Federal University of Minas Gerais, Brazil<\/b><\/td>\n<\/tr>\n

2:00-2:45 p.m.<\/b><\/td>\nAna Martinez, Biological Research Center (CIB), Spain<\/b>
\nFrom the theory to the bench in multitarget drugs for Alzheimer\u2019s disease therapy<\/b><\/a><\/td>\n		2:00-2:45 p.m.<\/b><\/td>\nIan Gilbert\u00a0\u00a0\u2013 University of Dundee, Scotland)<\/b>
\nDrug Discovery for Neglected Diseases<\/strong><\/a><\/em><\/b><\/td>\n<\/tr>\n
2:45-3:30 p.m.<\/b><\/td>\nHolger STARK (Heinrich-Heine- Univ. of Duesseldorf)<\/b>
\nHistamine H3<\/sub> Receptor Pharmacophores in Promising Multi-target Directed Ligands<\/strong><\/b><\/em><\/a><\/td>\n		2:45-3:30 p.m.<\/b><\/td>\nMaria Em\u00edlia Sousa (University of Porto, Portugal)<\/b>
\nOld Sources for New Antimicrobial Drugs: Lessons and Opportunities<\/strong><\/em><\/a><\/b><\/td>\n<\/tr>\n
3:30-3:45 p.m.<\/b><\/td>\nFlash Presentation: \u201cHeterocyclic multitargeting ligands of cholinesterases, histamine, and dopamine receptor subtypes: promising agents for cognitive dysfunctions\u201d – <\/b>Jo\u00e3o Paulo S. Fernandes (Federal University of S\u00e3o Paulo, Brazil)<\/a><\/td>\n3:30-3:45 p.m.<\/b><\/td>\nFlash Presentation: \u201cComputational Approach for the Rational Development of Inhibitors of NS5 methyltransferase Serotype 2-Dengue\u201d <\/b>– Natalia D\u00edaz Carpintieri (University of the Republic, Uruguay)<\/a><\/td>\n<\/tr>\n
3:45-4:15 p.m.<\/b><\/td>\nCoffee Break<\/td>\n3:45-4:15 p.m.<\/b><\/td>\nCoffee Break<\/td>\n<\/tr>\n
\n

Session 9: MedChem for Orphan Diseases<\/b><\/p>\n

Chair: Fl\u00e1vio Emery \u2013 University of S\u00e3o Paulo \u2013 Ribeir\u00e3o Preto, Brazil<\/b><\/td>\n

\n

Session 10: MedChem for Cancer<\/b><\/p>\n

Chair: Maria Em\u00edlia Sousa \u2013 University of Porto, Portugal<\/b><\/td>\n<\/tr>\n

4:15-5:00 p.m.<\/b><\/td>\nJean Leandro dos Santos (State University of S\u00e3o Paulo, Brazil)<\/b>
\nFetal hemoglobin inducers for Sickle Cell Disease<\/strong><\/em><\/a><\/b><\/td>\n		4:15-5:00 p.m.<\/b><\/td>\nPaulo R. Costa (Federal Univ. of Rio de Janeiro, Brazil)<\/b>
\nModified Isoflavonoids: Design, Synthesis and Antiproliferative Activity<\/a><\/strong><\/em><\/td>\n<\/tr>\n
5:00-5:45 p.m.<\/b><\/td>\nAngela Russel (University of Oxford, UK)<\/b>
\nDevelopment of next generation utrophin modulators for Duchenne muscular dystrophy: learning from clinical setbacks<\/a><\/span><\/b><\/td>\n		5:00-5:45 p.m.<\/b><\/td>\nAntonello Mai (University of Rome, Italy)<\/b>
\nTogether is Better: Epigenetic Polypharmacology<\/strong><\/em><\/b><\/a><\/td>\n<\/tr>\n
5:45-6:00 p.m.<\/b><\/td>\nFlash Presentation: \u201cIn Silico Study of the Free Energy of Binding of Kallikrein Inhibitors\u201d – <\/b>Wemenes J. L. Silva (Federal University of ABC, Brazil)\u00a0<\/span><\/a><\/td>\n5:45-6:00 p.m.<\/b><\/td>\nFlash Presentation: \u201cDevelopment of Dihydrodiazepinones as Inhibitors of the human Vaccinia-related Kinase 2 (VRK2)\u201d – <\/b>Marcela Campelo R. Silva (State University of Campinas, Brazil)<\/a><\/td>\n<\/tr>\n
6:00-7:00 p.m.<\/b><\/td>\nPoster Awards and BrazMedChem Awards (Previous Organizers)<\/i><\/td>\n<\/tr>\n
7:00-8:00 p.m.<\/b><\/td>\nClosing Ceremony<\/b><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n[\/vc_column_text][\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_column_text]Sunday, 25th September 2022 2:00-6:00 p.m. Conference Registration 9:00-12:00 a.m. Short course: Drug Design – Jean Leandro dos Santos Inova\u00e7\u00e3o em f\u00e1rmacos no ambiente acad\u00eamico com foco na otimiza\u00e7\u00e3o molecular 6:00-6:30 p.m. Opening Ceremony 12:00-2:00 p.m. Lunch 6:30-7:30 p.m. Opening Conference – Dr. Michael J. Sofia \u201cThe Discovery of Antivirals to Cure Chronic Viral Hepatitis\u201d…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-286","page","type-page","status-publish","hentry","entry","no-media"],"_links":{"self":[{"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/pages\/286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/comments?post=286"}],"version-history":[{"count":60,"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/pages\/286\/revisions"}],"predecessor-version":[{"id":778,"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/pages\/286\/revisions\/778"}],"wp:attachment":[{"href":"https:\/\/brazmedchem.org\/2022\/wp-json\/wp\/v2\/media?parent=286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}