ABSTRACT SUBMISSIONS POSTPONED
TO JULY 15, 2022
de 18 de abril a 19 agosto de 2022
BrazMedChem 2022 participants are cordially invited to contribute original research papers or reviews to this Special Issue of Pharmaceuticals. Gratuities will be granted for the first 4 accepted works (from participants of the Symposium) and special discounts on the publication fee for the others.
Implementation, development, biological evaluations and SAR of a library of polymethoxyflavones
Abstract : Mainly encountered within the Asteraceae, Rubiaceae and Rutaceae botanical families, polymethoxyflavones are a class of flavonoids with some strong reported biological activities. We have evaluated cytotoxic/chemosensitizing, anti-nociceptive, anti-parasite and enzyme inhibition effects. Sometimes associated with molecular docking studies, the obtained results have enabled to propose SAR and to identify hit compounds at the nanomolar to low micromolar range.