ABSTRACT SUBMISSIONS POSTPONED
TO JULY 15, 2022
Implementation, development, biological evaluations and SAR of a library of polymethoxyflavones
Abstract : Mainly encountered within the Asteraceae, Rubiaceae and Rutaceae botanical families, polymethoxyflavones are a class of flavonoids with some strong reported biological activities. We have evaluated cytotoxic/chemosensitizing, anti-nociceptive, anti-parasite and enzyme inhibition effects. Sometimes associated with molecular docking studies, the obtained results have enabled to propose SAR and to identify hit compounds at the nanomolar to low micromolar range.