Sunday, 25th September 2022
| 2:00-6:00 p.m. | Conference Registration | 9:00-12:00 a.m. | Short Course: Inovação em fármacos no ambiente acadêmico com foco na otimização molecular Jean Leandro dos Santos, pHD |
| 6:00-6:30 p.m. | Opening Ceremony | 12:00-2:00 p.m. | Lunch |
| 6:30-7:30 p.m. |
Opening Conference – Dr. Michael J. Sofia, PhD “The Discovery of Antivirals to Cure Chronic Viral Hepatitis” |
2:00-5:00 p.m. | Short Course: Inovação em fármacos no ambiente acadêmico com foco na otimização molecular Jean Leandro dos Santos, pHD |
| 7:30-11:30 p.m. | Welcome Cocktail |
Monday, 26th September 2022
| Session 1: Natural Products-based Drug Discovery | Session 2: Computer-aided Drug Design (CADD) | ||
| 9:00-9:45 a.m. | Scott Smid (University of Adelaide, Australia) The Phytochemical Diversity of Cannabis: Exploring this ‘Potpourri’ of Potential for Development of Cannabinoid-based medicines |
9:00-9:45 a.m. | Stefano Alcaro (Univ. Magna Græcia of Catanzaro, Italy) Can in silico Medicinal Chemistry help the drug discovery of natural compounds? |
| 9:45-10:15 a.m. | Lucindo Quintans (Federal Univ. of Sergipe, Brazil) Can we use terpenes in chronic pain models? How cyclodextrins can help it? |
9:45-10:30 a.m. | Alan Talevi, PhD – (University of La Plata, Argentina) LIDeB Tools: a Latin American resource of freely available, open-source cheminformatics apps to assist drug discovery projects |
| 10:15-10:45 a.m. | Laurent Picot (University of La Rochelle, France) Plant and algal natural products for tumor and antimicrobial phototherapy: an overview of species, photototoxic molecules and innovations. |
10:30-11:00 a.m. | Coffee Break |
| 10:45-11:15 a.m. | Coffee Break | 11:00-11:45 a.m. | Hugo Verli (Federal Univ. of Rio Grande do Sul, Brazil) How molecular flexibility can enhance drug discovery? |
| 11:15-11:45 a.m. | Raphael Grougnet (University of Paris Descartes, France) Implementation, development, biological evaluations and SAR of a library of polymethoxyflavones |
11:45-12:00 a.m. | Flash Presentation 2 – To be confirmed |
| 11:45-12:00 a.m. | Flash Presentation 1 – To be confirmed | 12:00-2:00 p.m. | Lunch |
| 12:00-2:00 p.m. | Lunch | ||
| Session 3: MedChem for Drug Addiction | Session 4: Pre-clinical Development | ||
| 2:00-2:45 p.m. | To be confirmed | 2:00-2:45 p.m. | Marco Aurélio Martins (Fiocruz, Brazil) Gold nanoparticles for the treatment of glucocorticoid insensitive asthma: what we have learned so far? |
| 2:45-3:30 p.m. | Frederico D. Garcia (Federal Univ. of Minas Gerais, Brazil) Preclinical and innovative uses of anticocaine vaccine: the UFMG-V4N2 |
2:45-3:30 p.m. | Stefan Laufer (University of Tübingen, Germany) DISCOVERY AND DEVELOPMENT OF A MKK-4 INHIBITORS TO INCREASE LIVER REGENERATION |
| 3:30-3:45 p.m. | Flash Presentation 3 – To be confirmed | 3:30-3:45 p.m. | Flash Presentation 4 – To be confirmed |
| 3:45-4:15 p.m. | Coffee Break | 3:45-4:15 p.m. | Coffee Break |
| Session 5: MedChem for Neglected Diseases | Session 6: MedChem for Neurodegenerative Diseases | ||
| 4:15-5:00 p.m. | Babu L. Tekwani (Southern Research, USA) Tricyclic endoperoxide dimers as promising leads for development of new drugs for drug-resistant Leishmaniasis* |
4:15-5:00 p.m. | Maria Laura Bolognesi (University of Bologna, Italy) Multi-target-directed ligands to combat neurodegenerative diseases — Past, present and future |
| 5:00-5:45 p.m. | Rafael Guido (University of São Paulo, Brazil) Discovery of Plasmodium falciparum Inhibitors as Lead Candidates for Malaria |
5:00-5:45 p.m. | Andrea Tarozzi (University of Bologna, Italy) Targeting the NLRP3 inflammasome in neurodegenerative diseases |
| 5:45-6:00 p.m. | Flash Presentation 5 – To be confirmed | 5:45-6:00 p.m. | Flash Presentation 6 – To be confirmed |
| 6:00-8:00 p.m. | Poster Session 1 | 6:00-8:00 p.m. | Poster Session 1 |
Tuesday, 27th September 2022
| BrazMedChem Awards | BrazMedChem – Scientific Activities for the Local Community | ||
| 9:00-9:30 a.m. | Young BrazMedChem Awards | 9:00-10:00 a.m. | Awards’ Ceremony of the BrazMedChem Writing Olympics |
| 9:30-10:30 a.m. | Vanguard BrazMedChem Awards | 10:00 a.m.- 6:00 p.m. | Scientific Activities |
| 10:30-11:00 a.m. | Senior BrazMedChem Awards | 2:00-3:00 p.m. | Theatrical Presentation for Local Community |
| 11:00-13:00 a.m. | Coffee Break/Poster Session 2 | ||
| 1:00-2:00 p.m. | Lunch | ||
| 2:00-7:00 p.m. | Free Time | ||
| 7:00-8:00 p.m. | Theatrical Presentation for BrazMedChem Community | ||
Wednesday, 28th September 2022
| Gender in Medicinal Chemistry: How to make a successfully career in Academy and Industry? | |||
| 9:00-9:20 a.m. | Speaker 1: Elizabeth Igne Ferreira (University of São Paulo) Medicinal Chemistry: advances and challenges |
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| 9:20-9:40 a.m. | Speaker 2: Maria Emília Sousa (University of Porto, Portugal) Research, Academia, and Outreach Activities in Portugal: a Personal Experience |
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| 9:40-10:00 a.m. | Speaker 3: Júlia L. Monteiro (EUROFARMA) Pre-Clinical Development at Eurofarma: how a Brazilian Pharmaceutical Company is investing in Drug Discovery? |
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| 10:00-10:30 a.m. | Discussion | ||
| 10:30 a.m.-12:30 p.m. | Coffee Break/Poster Session 3 | ||
| 12:30-2:00 p.m. | Lunch | ||
| Session 7: Multi-target Directed Ligands | Session 8: MedChem for infectious diseases | ||
| 2:00-2:45 p.m. | Ana Martinez, Biological Research Center (CIB), Spain From the theory to the bench in multitarget drugs for Alzheimer’s disease therapy |
2:00-2:45 p.m. | Ian Gilbert – University of Dundee, Scotland) Drug Discovery for Neglected Diseases |
| 2:45-3:30 p.m. | Holger STARK (Heinrich-Heine- Univ. of Duesseldorf) Histamine H3 Receptor Pharmacophores in Promising Multi-target Directed Ligands |
2:45-3:30 p.m. | Maria Emília Sousa (University of Porto, Portugal) Old Sources for New Antimicrobial Drugs: Lessons and Opportunities |
| 3:30-3:45 p.m. | Flash Presentation 7- To be confirmed | 3:30-3:45 p.m. | Flash Presentation 8 – To be confirmed |
| 3:45-4:15 p.m. | Coffee Break | 3:45-4:15 p.m. | Coffee Break |
| Session 9: MedChem for Orphan Diseases | Session 10: MedChem for Cancer | ||
| 4:15-5:00 p.m. | Jean Leandro dos Santos (State Univ. of São Paulo, Brazil) Fetal hemoglobin inducers for Sickle Cell Disease |
4:15-5:00 p.m. | Paulo R. R. Costa (University Rio de Janeiro, Brazil) Modified Isoflavonoids: Design, Synthesis and Antiproliferative Activity |
| 5:00-5:45 p.m. | Angela Russel (University of Oxford, UK) Development of next generation utrophin modulators for Duchenne muscular dystrophy: learning from clinical setbacks |
5:00-5:45 p.m. | Antonello Mai (University of Rome, Italy) Together is Better: Epigenetic Polypharmacology |
| 5:45-6:00 p.m. | Flash Presentation 9 – To be confirmed | 5:45-6:00 p.m. | Flash Presentation 10 – To be confirmed |
| 6:00-7:00 p.m. | Poster Awards and BrazMedChem Awards (Previous Organizers) | ||
| 7:00-8:00 p.m. | Closing Ceremony | ||
