Histamine H3 Receptor Pharmacophores in Promising Multi-target Directed Ligands Abstract: The classic “magic bullet” of Paul Ehrlich follows the rule: one disease – one reason – one drug. Modern therapeutic approaches have detected a number of different diseases caused by…
Together is Better: Epigenetic Polypharmacology Abstract: Recently, despite the great success achieved by the “magic bullets” in the treatment of different diseases through a marked and specific interaction with the target of interest, the pharmacological research is moving toward the…
Preclinical and innovative uses of anticocaine vaccine: the UFMG-V4N2 Abstract: The most promising strategy for treating cocaine addiction is an anti-cocaine vaccine. The treatment is based on the production of anti-cocaine antibodies, which blocks cocaine passage through the blood-brain barrier. The…
