Can we use terpenes in chronic pain models? How cyclodextrins can help it? Abstract: Brazilian biodiversity is estimated to represent about 20% of all biodiversity in the world, so its natural wealth is appreciable for several reasons: the discovery of…
Drug Discovery for Neglected Diseases Abstract: The Drug Discovery Unit (DDU) was set up at the University of Dundee in 2006. It is a fully integrated drug discovery unit, combining hit discovery, medicinal and computational chemistry, drug metabolism and pharmacokinetics.…
Research, Academia, and Outreach Activities in Portugal: a Personal Experience Abstract: Achieve gender equality and empower all women and girls is a Sustainable Development Goal (SDG) included in the 2030 Agenda for Sustainable Development, adopted by all United Nations Member…
Bio-orthogonal Reactions: Potential Tools of Current Medicinal Chemistry Hugo Cerecetto, PhD Summary The developments of the last decade in aqueous chemoselective reactions, bio-orthogonal reactions, for biomolecules modifications have provided tools to decorate them with some structural frameworks derived from probes,…
Antonello Mai graduated in Pharmacy in 1984 at the Faculty of Pharmacy of the University of Rome "La Sapienza" with 110/110 cum laude. In June 1992, he obtained the title of PhD in Pharmaceutical Sciences by discussing a thesis entitled…
Implementation, development, biological evaluations and SAR of a library of polymethoxyflavones Abstract : Mainly encountered within the Asteraceae, Rubiaceae and Rutaceae botanical families, polymethoxyflavones are a class of flavonoids with some strong reported biological activities. We have evaluated cytotoxic/chemosensitizing, anti-nociceptive, anti-parasite…
Old Sources for New Antimicrobial Drugs: Lessons and Opportunities Abstract: The decline of the output of the R&D programs of the pharmaceutical companies may have begun to turn around when compared to earlier years of the 21st century. Although one…
Gold nanoparticles for the treatment of glucocorticoid insensitive asthma: what we have learned so far? Abstract: Asthma is a chronic pulmonary disease that affects millions of people globally and can be fatal. 55% of asthmatics have inadequate control of their…
Minicurso - As aulas serão ministradas em português Inovação em fármacos no ambiente acadêmico com foco na otimização molecular Resumo: A capacidade transformadora da inovação em gerar novos produtos e processos é a forca motriz do desenvolvimento e estímulo à…
Thirty Years Seeking Drugs for Chagas Disease Abstract: Chagas disease, or American trypanosomiasis, an untreating parasitic disease that affect near to 6-7 million people worldwide. The illness is confined mainly in rural areas of 21 Latin American countries (excluding the…
